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10th Thuringian Biomaterials Colloquium

Lecture tip: Bacterial nanocellulose - A natural hydropolymer as a drug delivery system
Prof. Dr. Dagmar Fischer, Friedrich Schiller University, Chair of Pharmaceutical Technology, Jena, Germany

 

Abstracts:

Bacterial nanocellulose (BNC) represents an important source of energy due to its special properties such as high

purity and stability, excellent biocompatibility and high mechanical strength a
interesting carrier material, especially for innovative active ingredients. The three-dimensional network of cellulose fibers on the nanoscale opens up far-reaching interactions with numerous active substances. In the course of the investigations presented here, various techniques were developed to load BNCs with active substances in a highly efficient manner and to control their release in a targeted manner over periods ranging from a few hours to over a week. For this purpose, both laboratory-scale BNC and high-throughput generated BNC were used in comparison. The active ingredient used was octenidine, which is frequently used in wound treatment. The aim was to develop a ready-to-use system for acute and chronic dermal treatments.